More data about this group.
Last database update for these data: 2008-06-06 - Data extracted on 2009-04-14 from the database.
| Field | Value |
|---|---|
| Title | Construction of environmentally safe plant virus vectors |
| Participants | Erkki Truve (Leader) |
| Period | 2004 - 2007 |
| Description | We propose: i) to construct a new plant virus vector based on cocksfoot mottle sobemovirus (CfMV, an efficiently propagating virus with icosahedral particles which infects monocots growing in temperate pastures); ii) to insert strong antigenic determinants from animal pathogens into the constructed vector; iii) to immunise mice with CfMV-infected plant material; iv) to compare the efficiency of vaccines expressed from differently modified CfMV-based vectors; v) to test the potential of sobemoviruses to recombine in monocot hosts and map the hotspots of recombination; vi) to mutate the possible recombination hotspots in CfMV-based vector; vii) to test the modified CfMV-based vector for potential recombinations with naturally occurring sobemoviruses; viii) to screen Estonian fields and pastures for the possible occurrence of CfMV-related sobemoviruses. |
| Viruses | Cocksfoot mottle virus Ryegrass mottle virus Rice yellow mottle virus |
| Plants | Avena Hordeum vulgare Oryza sativa |
| Crops | Oats Barley Rice |
| Fundings | Estonian Science Foundation |